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April 17, 2017

Highlights at the 2017 AACR Annual Meeting in Washington, D.C.

The Center for Prostate Disease Research (CPDR) multi-disciplinary team - together with collaborators - presented 8 abstracts in moderated poster presentations at the American Association of Cancer Researchers Annual Meeting, April 1-5, 2017, SWashington, DC. The team was co-led by Dr. Shiv Srivastava, CPDR Co-Director and Professor in the Department of Surgery at USU and WRNMMC and Dr. Albert Dobi, Associate Director, CPDR and Research Assistant Professor, Department of Surgery , USU and WRNMMC.

AACR 2017 CPDR Team

Pictured (from left to right): Dr. Alagarsamy Srinivasan, Dr. Taduru Sreenath, Dr. Shashwat Sharad, Dr. Charles Xavier, Dr. Shiv Srivastava, Dr. Gyorgy Petrovics, Dr. Indu Kohaar, Dr. Albert Dobi, and Dr. Muhammad Jamal



Poster Presentations

Dr. Alagarsamy Srinivasan presented a poster titled: Secreted Protein Acidic and Rich in Cysteine (SPARC) Antigen and Autoantibodies in Sera of Prostate Cancer Patients: Potential Use in Diagnosis /Prognosis

Dr. Taduru Sreenath presented a poster titled: Ets Related Gene Driven Androgen Receptor Aggregation is a Key Regulator of Endoplasmic Stress During Prostate Carcinogenesis

Dr. Ahmed Mohamed presented a poster titled: Structure-Activity Relationship Studies, Synthesis and Evaluation of Derivatives of ERGi-USU, a Selective Inhibitor of ERG Positive Cancer Cells

Dr. Indu Kohaar presented 2 posters titled: Development of a Race/Ethnicity Informed Gene Expression Panel with Potential to Improve Prostate Cancer Diagnosis and Association of Common Genetic Variants with TMPRSS2-ERG Fusion Status in Prostate Cancer

Dr. Hua Li presented a poster titled: Generation and Characterization of Prostate Specific Pmepa1 Conditional Knockout Mouse Model

Dr. Shashwat Sharad presented a poster titled: Distinct Expression and Biological Functions of PMEPA1 Isoforms in Prostate Cancer in the Context of Androgen and TGFβ Signaling

Kevin Babcock presented a poster titled: Biological Functions of LSAMP, a Gene at the 3q13.31 Locus, Associated with Higher Frequency of Deletions in African American Prostate Cancers


Poster Presentations of Collaborative Studies

Dr. Shobha Ravipaty (Berg Pharma) presented a poster titled: Clinical validation of a serum protein panel (FLNA, FLNB and KRT19) for diagnosis and prognosis of prostate cancer

Dr. Michael A. Kiebish (Berg Pharma) presented a poster titled: A serum multiomics signature for enhancing prostate cancer diagnosis and prognosis

Dr. Hui Wang (Pacific Northwest National Laboratory) presented a poster titled: Verification of Prostate Cancer Genomic Biomarker Candidates at Protein Level Using PRISM-SRM

Dr. Hong Li (Shanghai Institutes for Biological Science) presented a poster titled: Collaborative Analyses for Delineating Mutation Variations among Different Ethnic Patient Groups of Prostate Cancer Based on Genomic Data Integration

Dr. Parameet Kumar (Uniformed Services University) presented a poster titled: Comparative RNA-Seq Analysis Reveals Dysregulation of Major Canonical Pathways in ERG-inducible LNCaP Cells