basic sceince research

MULTI-CENTER NATIONAL DATABASE PROGRAM

Understanding the Fight Against Prostate Cancer

Currently, little is known about the causes of prostate cancer development. Only advanced age, family history, and race/ethnicity have been established as risk factors for cancer development. There is continued debate over the value of annual PSA screening in asymptomatic men or treatment in men with low risk disease. Such debate can be confusing for patients -- and not all experts agree on these important topics.

Leveraging Programmatic Strengths to Improve Patient Outcomes

The Center for Prostate Disease Research (CPDR) Multi-center National Database Program seeks to longitudinally collect comprehensive demographic, clinical, treatment and quality of life outcomes data to learn more about prostate disease, particularly prostate cancer, in an effort to better prevent, diagnose and treat patients. The database is a highly valuable programmatic resource that enables CPDR researchers to examine patients diagnosed in an equal access health care system, who are characterized by racial/ethnic heterogeneity. Patient data are linked to bio-specimens including urine, serum, and tissue providing opportunity to examine important translational research questions, including biomarkers of disease detection and progression.

 

MISSION

  • Obtain informed consent to enroll men with prostatic diseases for longitudinal follow-up
  • To capture comprehensive clinico-pathologic, demographic, and longitudinal follow-up data including treatment outcomes, as part of routine data collection activities
  • To assess at regular intervals the health-related quality-of-life of patients, along the continuum of prostate disease care
  • To serve as a critical link in support of basic science and clinical science research, providing unprecedented opportunities for translational research
  • To provide a resource for training and education of medical residents and students
  • To provide a national resource for prostate disease researchers, supporting breakthroughs in studies on prostate disease prevention, diagnosis, and treatment

 

Unique attributes of the database include a study population comprised primarily of military health care beneficiaries with comparable access to health care and uniformity in PSA screening and treatment guidelines; an over-representation of African American men, allowing for in-depth examination of the impact of race/ethnicity on prostate cancer outcomes; abundant clinical data necessary to calculate risk factors for disease development and progression, including PSA kinetics (e.g., doubling time, velocity) and obesity; (robust, long term data on health-related quality-of-life outcomes during the period of cancer survivorship; and a civilian site that can serve as an internal control study population.

MNDP Staff Listing | CDPR Sites

CURRENT EVENTS


March 20, 2014

Collaborative Summer Training Program for HBCU Undergraduates in Washington, DC

Dr. Shiv Srivastava received an FY07 PCRP Collaborative Undergraduate HBCU Student Summer Training Program award to provide foundational cancer research opportunities for undergraduates at the University of the District of Columbia (UDC) through the Uniformed Services University of the Health Sciences (USUHS) – Center for Prostate Disease Research (CPDR). In this collaborative effort, Dr. Deepak Kumar served as the Partnering Principal Investigator at UDC. This program allowed UDC students with limited to no exposure in biomedical research to gain experience in state-of-the-art prostate cancer translational research.

Read the full Article in the Congressionally Directed Medical Research Programs (CDMRP) Prostate Cancer Reseach Program Brochure (pg 13).

 

 

CPDR April 2015
Distinguished Visiting Professor


Deborah Winn, Ph.D.

Deputy Director
Division of Cancer Control and Population Sciences
National Cancer Institute

Presentation: "Waterpipes and Health Effects:
Challenges of Studying Emerging
Tobacco-related Behaviors"

Date: April 2, 2015
Time: 1100 - 1200
Location: CPDR, Rockville, MD
2nd floor conference room

 

WRNMMC UsToo!
May 2015 Guest Speaker


CAPTAIN Timothy Donahue, MD

Presentation: "Rising PSA after Treatment for Prostate Cancer"

Date: 7 May 2015
Time: 7-8:30 PM
Location: WRNMMC, America Building, 2nd floor, Room 2525
Contact: COL (ret) Jane Hudak for more information at 301-319-2918 or
jane.l.hudak.ctr@mail.mil

(The presentation also may be viewed via video teleconference at the Fort Belvoir Community Hospital. Go to the Oaks Pavilion, 1st floor, Room 332, to participate.)

Read the February 2015 WRNMMC UsToo! Newsletter