BASIC SCIENCE RESEARCH PROGRAM
Innovative Techniques Through Basic Science Research
The Basic Science Research Program (BSRP) focuses on defining prostate cancer-specific molecular alterations that would lead to better understanding of the causes of prostate cancer. Prostate cancer gene discovery and biology focused research efforts are complemented by collaborations from the CPDR's Clinical Research and Multicenter National Database programs, accelerating the evaluations of new biomarkers and therapeutic targets with potential in enhancing the management of prostate cancer.
The program is led by Dr. Shiv Srivastava, who is an internationally recognized leader in the field of cancer research. Strong collaborations with Dr. Isabell A. Sesterhenn from JPC (formerly AFIP) and the CPDR-Clinical Research Program at WRNMMC (formerly WRAMC) remains the mainstay of the highly productive translational research initiatives. Due to the reorganization of the AFIP as JPC, Dr. Sesterhenn's laboratory has been integrated within the CPDR-BSRP as of August 2011.
- Discovery of frequent and potentially causal prostate cancer gene alterations using cutting edge technologies and well annotated and precisely processed bio-specimens
- Evaluation of cancer biology of prostate cancer relevant genes or proteins using established and new experimental models
- Development of new molecular strategies for improving prostate cancer diagnosis (more cancer specific markers than PSA) and prognosis Contents are Proprietary and Provided for CPDR Scientific Advisory Committee Review Only 1: 5
- Delineation of hormonal mechanisms involved in prostate cancer onset or progression
- Development and evaluation of novel molecular therapeutic agents for prostate cancer
- Identification of molecular determinants of prostate cancer susceptibility in high-risk groups such as African-Americans
- Development and maintenance of long-term molecular specimen resources for translational investigations at CPDR and collaborations at other institutions
- Education and training of next generation of basic science and translational researchers in prostate cancer
Education and training of medical and graduate students, post-doctoral fellows, residents and visiting scientists in CaP research Two of the major activities of the BRP research program include investigator-initiated research and development of unique bio-resources critical for research at CPDR and in the CaP field.
Guest Speaker Program
Dr. Jim David
Board certified psychotherapist in private practice treating individuals, couples and families
Presentation: "The ABC’s of Self-Care"
Date: Thursday 2 Feb 2017
Location: Walter Reed National Military Medical Center (America Building, 2nd floor, Room 2525) and Fort Belvoir Community Hospital (via video teleconference in Oaks Pavilion, 1st floor, Room 332).
A military ID card is required to get on base at Walter Reed. Attendees without a military ID need to call the Prostate Center at 301-319-2900 at least 4 business days in advance to complete paperwork for gate access approval. Also bring some form of picture identification at the gate.
Snow day: If the federal government is closed the day of the presentation, the program is cancelled. If the federal government has a delayed opening that day, the show will go on! Call the Prostate Center at 301-319-2900 if you have any questions.
Read the January 2017 CPDR E-Newsletter
June 23, 2016
by Paula Amann
Published in the June 2016 issue of Military Medical Research News, a monthly newsletter of the Department of Research Programs, Walter Reed National Military Medical Center.
Fine-tuning facial transplants, predicting bone fractures, shrinking prostate cancers with new drugs and cutting the costs of surgical training with the right technology: These were among the problems probed by competition winners for 2016 Research and Innovation Month at Walter Reed National Military Medical Center (WRNMMC).
RAP winners included LT Daniel Griffin, MC (resident laboratory category); CPT Sarah Placek, MC (resident clinical); Charles P. Xavier, Ph.D. (staff laboratory); and Benjamin Sheffield (staff clinical).