BASIC SCIENCE RESEARCH PROGRAM
Innovative Techniques Through Basic Science Research
The Basic Science Research Program (BSRP) focuses on defining prostate cancer-specific molecular alterations that would lead to better understanding of the causes of prostate cancer. Prostate cancer gene discovery and biology focused research efforts are complemented by collaborations from the CPDR's Clinical Research and Multicenter National Database programs, accelerating the evaluations of new biomarkers and therapeutic targets with potential in enhancing the management of prostate cancer.
The program is led by Dr. Shiv Srivastava, who is an internationally recognized leader in the field of cancer research. Strong collaborations with Dr. Isabell A. Sesterhenn from JPC (formerly AFIP) and the CPDR-Clinical Research Program at WRNMMC (formerly WRAMC) remains the mainstay of the highly productive translational research initiatives. Due to the reorganization of the AFIP as JPC, Dr. Sesterhenn's laboratory has been integrated within the CPDR-BSRP as of August 2011.
- Discovery of frequent and potentially causal prostate cancer gene alterations using cutting edge technologies and well annotated and precisely processed bio-specimens
- Evaluation of cancer biology of prostate cancer relevant genes or proteins using established and new experimental models
- Development of new molecular strategies for improving prostate cancer diagnosis (more cancer specific markers than PSA) and prognosis Contents are Proprietary and Provided for CPDR Scientific Advisory Committee Review Only 1: 5
- Delineation of hormonal mechanisms involved in prostate cancer onset or progression
- Development and evaluation of novel molecular therapeutic agents for prostate cancer
- Identification of molecular determinants of prostate cancer susceptibility in high-risk groups such as African-Americans
- Development and maintenance of long-term molecular specimen resources for translational investigations at CPDR and collaborations at other institutions
- Education and training of next generation of basic science and translational researchers in prostate cancer
Education and training of medical and graduate students, post-doctoral fellows, residents and visiting scientists in CaP research Two of the major activities of the BRP research program include investigator-initiated research and development of unique bio-resources critical for research at CPDR and in the CaP field.
March 20, 2014
Collaborative Summer Training Program for HBCU Undergraduates in Washington, DC
Dr. Shiv Srivastava received an FY07 PCRP Collaborative
Undergraduate HBCU Student Summer Training
Program award to provide foundational cancer research
opportunities for undergraduates at the University of
the District of Columbia (UDC) through the Uniformed
Services University of the Health Sciences (USUHS) –
Center for Prostate Disease Research (CPDR). In this
collaborative effort, Dr. Deepak Kumar served as the Partnering Principal Investigator at UDC. This program allowed
UDC students with limited to no exposure in biomedical research to gain experience in state-of-the-art prostate cancer
Read the full Article in the Congressionally Directed Medical Research Programs (CDMRP) Prostate Cancer Reseach Program Brochure (pg 13).
CPDR April 2015
Distinguished Visiting Professor
Deborah Winn, Ph.D.
Division of Cancer Control and Population Sciences
National Cancer Institute
Presentation: "Waterpipes and Health Effects:
Challenges of Studying Emerging
Date: April 2, 2015
Time: 1100 - 1200
Location: CPDR, Rockville, MD
2nd floor conference room
May 2015 Guest Speaker
CAPTAIN Timothy Donahue, MD
Presentation: "Rising PSA after Treatment for Prostate Cancer"
Date: 7 May 2015
Time: 7-8:30 PM
Location: WRNMMC, America Building, 2nd floor, Room 2525
Contact: COL (ret) Jane Hudak for more information at 301-319-2918 or
(The presentation also may be viewed via video teleconference at the Fort Belvoir Community Hospital. Go to the Oaks Pavilion, 1st floor, Room 332, to participate.)